As of my last update, here are some of the top universities in Spain, known for their academic excellence, research contributions, and overall reputation:

1. University of Barcelona (Universitat de Barcelona): Renowned for its comprehensive range of programs, including arts and humanities, sciences, engineering, and health sciences.
2. Complutense University of Madrid (Universidad Complutense de Madrid): One of the oldest universities in the world, offering a wide array of disciplines and recognized for its research output.
3. University of Granada (Universidad de Granada): Known for its strong emphasis on research, with notable programs in sciences, humanities, and social sciences.
4. Autonomous University of Barcelona (Universitat Autònoma de Barcelona): Highly regarded for its innovative research and interdisciplinary approach to education across various fields.
5. University of Valencia (Universitat de València): A leading institution known for its excellence in teaching and research, particularly in the fields of science, health sciences, and social sciences.
6. Pompeu Fabra University (Universitat Pompeu Fabra): Recognized for its focus on social sciences, humanities, communication, and economics, with a reputation for academic rigor and innovation.
7. University of Navarra (Universidad de Navarra): A private university known for its strong emphasis on research, particularly in business, law, and medicine.
8. University of Santiago de Compostela (Universidade de Santiago de Compostela): One of the oldest universities in Spain, acclaimed for its research contributions and cultural heritage.
9. Autonomous University of Madrid (Universidad Autónoma de Madrid): Known for its research excellence and vibrant academic community, offering programs across a wide range of disciplines.
10. University of Seville (Universidad de Sevilla): A prestigious institution with a long history of academic excellence, offering diverse programs in sciences, humanities, and social sciences.

These universities represent just a glimpse of Spain’s rich academic landscape, with many other institutions across the country offering high-quality education and research opportunities. Rankings may vary depending on the criteria used and the year of assessment, so it’s always a good idea to consult multiple sources when evaluating universities.